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How LSD Dissolves the Sense of Self

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How LSD Dissolves the Sense of Self
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3/26/18 10:36 PM
Ran across this article today. It describes a study at the University of Zurich where people were given LSD and an inhibitor, Ketanserin, which is known to block specific serotonin receptors. Then they were monitored in a MRI scanner while performing some activities with an avatar. The study found evidence that a specific neuroreceptor (5-HT2A) is involved in constructing the sense of self.

RE: How LSD Dissolves the Sense of Self
Answer
3/27/18 1:35 AM as a reply to svmonk.
So basically the right neuroreceptor (5-HT2A) agonist/antagonist can make people enlightened or at least temporarily? It's time to stop meditating then! emoticon emoticon

RE: How LSD Dissolves the Sense of Self
Answer
3/27/18 9:33 AM as a reply to svmonk.
Hi 

This is interesting. I wonder wether this has implications for the use of certain anti-depressants in meditators. 

I am no expert. But some anti-depressants are 5HTA antagonists, which according to this would highten the self sense (opposite to LSD which is an agonist). 

So this  includes Trazadone and Remeron. 

Following this line. If a meditator was aiming at no-self experience, this class of drugs may hamper progress. Not sure, but its interesting...

B